In 2020, news headlines repeated John Moult’s words at the end of a stunning competition: Artificial intelligence had “solved” a long-standing grand challenge in biology, protein structure prediction.
Scientists from Scripps Research have uncovered new structures of transthyretin, a protein that moves important hormones like thyroxine through blood and spinal fluid. Misfolded versions of the ...
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Machine Learning Applications in Predicting Protein Structures
Machine learning (ML) is transforming protein structure prediction. Algorithms can predict 3D structures from amino acid ...
Deciphering the building blocks of life has long been a painstaking process, but now a quiet revolution in computing power is changing everything – with research at the University of Otago’s Faculty ...
The tiny protein known as transthyretin can cause big problems in the body when it misfolds after secretion. While healthy transthyretin moves hormones through blood and spinal fluid, misfolded ...
When a protein folds, its string of amino acids wiggles and jiggles through countless conformations before it forms a fully folded, functional protein. This rapid and complex process is hard to ...
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