Biologists are very interested in how proteins, lipids and other compounds are organized and interact in systems. Very few organizational details can be gained by using standard transmission-based ...

Microscopy continues to transform the life sciences. Here are five recent breakthroughs made possible by the technique.

Computational fluorescence microscopy (CFM) requires accurate point spread function (PSF) characterization for high-quality ...

Using a tiny, spherical glass lens sandwiched between two brass plates, the 17th-century Dutch microscopist Antonie van Leeuwenhoek was the first to officially describe red blood cells and sperm cells ...

Fluorescent nanodiamonds (FNDs) possess unique characteristics, including high biological compatibility, infinite photostability, the absence of photoblinking, a long fluorescence lifetime (>10 ns), ...

Researchers have reported a sample-prior-based approach to point spread function decoupling that improves system ...