Biological tissues are made up of different cell types arranged in specific patterns, which are essential to their proper ...

Mapping biological networks in lung adenocarcinoma using transcriptomic analysis to identify prognostic biomarkers and therapeutic targets.

Conventional transcriptomic techniques have revealed much about gene expression at the population and single-cell level—but they overlook one crucial factor: spatial context. In musculoskeletal ...

Spatial transcriptomics is a technique that provides information about gene expression patterns within intact tissues. This technology employs various methodologies, including in situ sequencing (ISS) ...

Single-cell RNA transcriptomics allows researchers to broadly profile the gene expression of individual cells in a particular tissue. This technique has allowed researchers to identify new subsets of ...

Spatial transcriptomics, however, measures RNA expression in space, within a given tissue sample. Open-ST offers a cost-effective, high-resolution, easy-to-use method that captures both tissue ...

This eBook cuts through the complexity of spatial techniques, featuring a series of interviews with pioneers in the field, and peer-reviewed research from the Taylor & Francis journal portfolio. This ...

Spatial transcriptomics offers a revolutionary approach to understanding the tumor microenvironment (TME) in solid tumors by preserving the spatial context of gene expression, which is crucial for ...

This figure shows how the STAIG framework can successfully identify spatial domains by integrating image processing and contrastive learning to analyze spatial transcriptomics data effectively.