CHICAGO -- The choice between furosemide and torsemide didn't matter for longer-term clinical outcomes of hospitalized heart failure patients, according to the comparative effectiveness trial ...

This study was undertaken to determine the relative effectiveness of chlorothiazide, spironolactone ∥ and a combination of both drugs as diuretic agents and to investigate the effect of spironolactone ...

Please provide your email address to receive an email when new articles are posted on . CHICAGO — A treatment strategy of torsemide vs. furosemide did not improve long-term clinical outcomes for ...

Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Loop diuretics are widely used in the management of edema and heart failure. They are also widely misunderstood. The reason is this: Loop diuretics are often prescribed in a dose-dependent strategy.

Bioassays are critical for determining drug substance and drug product potency, which is why it is important to understand the fundamentals of developing an effective bioassay. A bioassay measures ...

Diuretics are agents commonly used in diseases characterized by excess extracellular fluid, including chronic kidney disease, the nephrotic syndrome, cirrhosis and heart failure. Multiple diuretic ...

Diuretics are in the forefront of the antihypertensive armamentarium and constitute the reference antihypertensive drugs. This is so because monopharmacotherapy with these substances lowers high blood ...