Using a novel method, Weizmann Institute of Science researchers map 16 types of simultaneous changes in dozens of samples; ...

A chemical modification in the HIV-1 RNA genome whose function has been a matter of scientific debate is now confirmed to be key to the virus's ability to survive and thrive after infecting host cells ...

RNA plays critical roles in nearly all biological processes, but current methods for sequencing RNA are significantly limited. This is partially because RNA molecules are chemically modified within ...

A new tool called SigRM helps researchers study RNA modifications in individual cells, improving our understanding of how genes are regulated. Researchers have developed a new tool that will help ...

Cancer, a disease with global impact, is intricately linked to dysregulated gene expression, which is influenced by both genetic mutations and epigenetic changes, including RNA modifications. A ...

CRISPR-Cas13, a powerful RNA-targeting technology is gaining increasing attention as a next-generation gene therapy platform due to its precision and reduced side effects. Utilizing this system, ...

The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

Hummingbird Diagnostics GmbH, a pioneer in harnessing blood-based small RNAs for early disease detection and characterization, today announced the publication of a new study in Nature Communications ...

Cancer cells are metabolic opportunists, bending every pathway to fuel unchecked growth. Now UCLA scientists show that a single protein—Insulin-like Growth Factor 2 mRNA-Binding Protein 3 ...