A new single-cell profiling technique has mapped pre-malignant gene mutations and their effects in solid tissues for the ...

Mutations in the tumor suppressor TP53 are a common cause of cancer, making the altered protein an attractive target for ...

GLOBAL: Australian researchers have discovered that a single mutation in the DNA sequence for a methylation enzyme dysregulates key tumour-suppressing pathways, opening up new avenues for blood cancer ...

Researchers at USC have developed a yeast model to study a gene mutation that disrupts the duplication of DNA, causing massive damage to a cell's chromosomes, while somehow allowing the cell to ...

DNA doesn’t just sit still inside our cells — it folds, loops, and rearranges in ways that shape how genes behave.

Researchers have discovered a mechanism in DNA that regulates how disease-causing mutations are inherited. The team identified two enzymes that regulate a chemical modification, 6mA, in mitochondrial ...

Researchers developed a single-cell sequencing method that simultaneously measures cancer-linked DNA mutations and gene ...

Mitochondria are well known as the powerhouses of the cell because of their energy generating capabilities. These little organelles are very special, because they also carry their own tiny little ...

Only around two percent of the human genome codes for proteins, and while those proteins carry out many important functions of the cell, the rest of the genome cannot be ignored. However, for decades ...