The liver has a unique structure, especially at the level of individual cells. Hepatocytes, the main liver cells, release bile into tiny channels called bile canaliculi, which drain into the bile duct ...
Until now, doctors knew hepatic stellate cells mainly as drivers of liver fibrosis. The actual functions of this cell type have hardly been studied to date. Researchers have now determined that ...
A novel 3D cell culture method has been developed that encourages liver progenitor cells to self-organize and form blood vessel networks for the first time. The development of accurate liver organoids ...
Liver disease is a major global health problem, causing over two million deaths worldwide each year. While animal models have helped to understand liver biology, they often fail to accurately ...
(A and B) Formalin-fixed, paraffin-embedded liver sections from 8~10 weeks old C57BL/6J mice were sequentially stained with markers as indicated. The upper panel shows the representative staining of ...
Hepatic stellate cells (HSCs) are activated to heal the liver when it has a lesion (such as fibrosis or fatty liver); their function is to protect the liver by producing an extracellular matrix ...
In a highly collaborative, cross-institutional ImPLANT project funded by the Advanced Research Projects Agency for Health (ARPA-H) Personalized Regenerative Immunocompetent Nanotechnology Tissue ...
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