New research has uncovered a complex interplay between extracellular matrix (ECM) structure and the transcriptional responses of cancer cells, showing how they alter their gene expression to ‘escape’ ...
Between and around the billions of neurons in the human brain is an equally vital scaffold, the extracellular matrix (ECM). An interlinked net of proteins and sugars that surrounds brain cells, the ...
In cell and animal models of amyotrophic lateral sclerosis (ALS), the expression of toxic dipeptides in neurons led to changes in the extracellular matrix (ECM) as a protective response. The authors ...
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