technologynetworks

Kinetic Constants and Sample-to-Sample Variation in the Rate of Metabolism of two or more Substrates for Human Liver Microsomal CYP1A2, CYP2B6, CYP2C8, CYP2D6 and CYP3A4/5

Marker substrates for certain CYPs have changed for several reasons, including the need for improved selectivity and sensitivity, reliable substrates for LC/MS/MS analysis, and substrates that provide ...
Nature

Regression diagnostics

Residual plots can be used to validate assumptions about the regression model. Figure 1: Residual plots are helpful in assessments of nonlinear trends and heteroscedasticity. A formal test of lack of ...
JSTOR Daily

The Effect of Retaining Probability Variation on Sample Size Calculations for Normal Variates

Skalski (1992, Biometrics 48, 877-882) assumed a constant retaining probability p for all experimental units and found that the traditional ad hoc procedure of escalating sample size by the ...
JSTOR Daily

Numerical Solution of Stochastic Differential Equations with Constant Diffusion Coefficients

Mathematics of Computation, Vol. 49, No. 180 (Oct., 1987), pp. 523-542 (20 pages) We present Runge-Kutta methods of high accuracy for stochastic differential ...