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Lipid nanoparticle structure shapes cell uptake: Cubosomes fuse with membranes for efficient delivery
Scientists have discovered that the internal shape of tiny drug-delivery particles—called lipid nanoparticles—has a big impact on how well our cells absorb them, paving the way to more efficient ...
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Unexpected asymmetry in lipid bilayer challenges understanding of mammalian cell membranes
Lipid bilayers in mammalian membranes can have a more asymmetric composition than previously thought, new research shows. This lipid abundance asymmetry is enabled by the unique properties of ...
Schematic illustration showing the classification of lipid‐based nanocarriers (LBNCs) (including liposomes, micelles, nanoemulsions, SLNs/NLCs, LNPs, BLNs, SRLNCs) and their targeted delivery to ...
Researchers have studied the cell membranes of ctenophores ('comb jellies') and found they had unique lipid structures that allow them to live under intense pressure. The bottom of the ocean is not ...
In a recent study published in the journal Cell, researchers identify lipidomes as four cluster of differentiation 1 (CD1) antigen-presenting molecules and, as a result, reveal a map of self-lipid ...
A review maps high throughput strategies that link automation, microfluidics, and barcoding into a unified pipeline, enabling faster, more predictive lipid nanoparticle development for genetic ...
In silico antibody accessibility analysis indicates that ectodomain epitopes are transiently exposed, while MPER epitopes are virtually always occluded in the pre-fusion trimer.
In a recent study published in Cell Host & Microbe, researchers highlighted the role of lipids, especially bacteria-derived lipids in the gut microbiome, in mammalian physiology in the context of ...
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