Researchers have discovered how cells activate a last-resort DNA repair system when severe damage strikes. When genetic ...

New research reveals that triggering a cell’s DNA damage response could be a promising avenue for developing novel treatments against several rare but devastating viruses for which no antiviral ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular aging, cancer, ...

MSK researchers are shedding new light on G-quadruplexes, a type of secondary DNA structure that can cause DNA replication to stall. The structures are a potential therapeutic target in cancer. Image ...

One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published ...

A new study shows, for the first time, how the human genome folds and moves in 3D over time to control when genes turn on and ...

A team of researchers has generated one of the most detailed 3D maps of human chromosomes, cataloging over 140,000 DNA looping interactions.

Researchers at the CNIO show that oestrogens regulate gene expression by changing DNA supercoiling. Hormone-activated ...

Most of an animal cell’s DNA is stored in its nucleus, packaged into chromosomes that help maintain order. But cancer cells often carry another type of DNA: molecules separate from the rest of the ...