Through comprehensive genomic and immune analyses, mechanisms of lung cancer resistance after treatment with EGFR inhibition and vaccine therapy were investigated. This case report, together with data ...
Gastrointestinal (GI) cancers represent a complex interplay of genetic mutations, epigenetic alterations, and environmental factors. The initiation and progression of these cancers are influenced by ...
Clonal hematopoiesis of indeterminate potential (CHIP) is an age-related condition associated with increased mortality among patients with cancer. CHIP mutations with high variant-allele frequencies ...
Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...
Efficacy and safety of durvalumab plus tremelimumab versus standard chemotherapy for non-small cell lung cancer: A systematic review and meta-analysis of phase III randomized controlled trials. This ...
Clinical Utility of Molecular Tumor Board Review for Identification of Possible Germline Pathogenic Variants on Tumor Next-Generation Sequencing Reports We demonstrate dynamic evolution of resistance ...
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Clonal hematopoiesis linked to increased heart disease risk in cancer patients receiving treatment
About 1 in 5 patients with cancer who undergo genetic testing are incidentally found to have mutations in their blood called ...
A study unveils a newly constructed immune map, highlighting the distinct immune infiltrate patterns in pancreatic tumors. These findings could pave the way for tailored immunotherapies and improved ...
Tumor-infiltrating clonal hematopoiesis (TI-CH) increased the risk of disease recurrence or death among patients with early non-small cell lung cancer (NSCLC), and the risk of death from any cause ...
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